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Gardasil 9: Does it better than the Gardasil 4?

Gardasil 9: Does it better than the Gardasil 4?
FB Dr Soarawee
Soarawee Weerasopone, MD

Andrologist
Royal Phnom Penh hospital, Kingdom of Cambodia

When lots of patients in my office who asked about what the differences between these HPV vaccination, Gardasil 9 and Gardasil 4. In this article it will answer for all those questions in the details.

Gardasil 9: Does it better than the Gardasil 4?
Several gentlemen are questioned on Gardasil 9 vaccination.

Gardasil 9 FAQ.

Which HPV subtype could have been protected from?

  • Gardasil 4 has a protection against HPV 6, 11, 16 and 18.
  • Gardasil 9 has a protection against HPV 6, 11, 16, 18, 31, 33, 45, 53 and 58.

How much efficacy rating which can be protected from cervical cancer?

  • Gardasil 4 has been reported around 70% protection against cervical cancer.
  • Gardasil 9 has been reported around 90% protection against cervical cancer.
Gardasil 9: Does it better than the Gardasil 4?
Gardasil 9 can protect Gentlemen against penile cancer.

How about the protection rate against penile cancer in gentlemen?

  • Still haven’t the well-constructed literatures on Gardasil injection for male yet. But, the currently evidence show that Gardasil injection has benefit on HPV protection yet lower in cost-effectiveness than female vaccination.

How about the protection rate of a genital warts?

  • Gardasil 4 has been reported around 77% protection against genital warts.
  • Gardasil 9 has no any updated the efficacy of against genital warts yet, but more protection rate than Gardasil-4 is prospected.

Since 1 complete course of Gardasil injections are 3 jabs in total (0, 2 and 6 months). Can we get any protection from the first jab?

  • Yup! You can get somewhat protection immediately after the first jab. There was a paper from Spain since 2017 that 61% protection rate can be received at a single Gardasil-4 shot, but there’s no a clearer report on how much it will last.
Gardasil 9: Does it better than the Gardasil 4?
Patient still get benefit from Gardasil 9 even had previously HPV infection.

Will patients who previously had a history of HPV infection still get benefit for the Gardasil vaccination?

  • Absolutely, yes! There was a good literature on 2009 which studied in 18,174 women and the result came up as Gardasil can give such protection even had previously being infected.

Gardasil 9 is a bit costly if comparing to the Gardasil 4, so you’re be able to make consideration over an options based on the above information which I was given. Any question, talk to your trusted urologist, or it would be my honor if you text me. Take care!

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