Varicocele treatment: An oral medication role

Varicocele treatment : An oral medication role

As I have been discussed about the varicocele disease which is able to affect male’s fertilization in the beginning.  I also have mentioned that the most gentlemen who experienced in this problem, finally, will end up by a surgical correction. This topic will be shown another alternative oral medication that could possibly improve on symptomatic varicocele treatment.

You can visit my Varicocele article here.

Varicocele treatment : An oral medication role
The Varicocele causing infertility and testicular discomfort.

At the beginning, we must know for how the varicocele harms us. Normally, the testicle function well with the temperature around 35 degrees centigrade. When varicocele introduces venous back flow to the affected testis, bringing the blood which is temperature around 37 degrees centigrade, as equally to the core temperature, it raises up the testicular temperature, then causing infertility and testicular discomfort.

Varicocele treatment : An oral medication role
The varicocele pathophysiology is just like the varicose vein which happen at the leg.

Let’s get back to the role of an oral medication in varicocele treatment! From literatures I have reviewed, there is only one scientific-approved tablet name “Micronized purified flavonoid fraction” or MPFF, which help improve on symptomatic varicocele. MPFF improves venous tone and contractility and decreases venous blood pressure. Normally, vascular surgeons use MPFF in varicose veins of lower extremities.

Varicocele treatment: An oral medication role
Symptomatic varicocele can be improved with oral medication.

Varicocele treatment: Oral medication strategy

There was a literature showing a trial on MPFF since 2005 and here is the result.

  1. Testicular discomfort – after 6 months of MPFF oral medication
    • 87.5%  more likely free from testicular discomfort
    • 12.5%  more likely improved testicular discomfort
  2. Infertility – after 6 months of MPFF oral medication
    • Significantly improve sperm motility
    • Not improve in semen volume, semen concentration or morphology

MPFF might be a good alternative oral treatment for varicocele pain control for someone who wanted to avoid surgical management. But it seems like not so work on the improvement of the sperm quality. Any questions, you can discuss with your trusted andrologist or it would be my honor if you text me.

You can visit my official website here!

Free 1
Free 2
WhatsApp BW 3
Telegram Final

Topics on Men’s health

Paraphimosis: True Urologic emergency

Paraphimosis: True Urologic emergency

The paraphimosis is one among another urologic emergency issue that I’ve been experienced frequently at the emergency room. It is a condition when the penile foreskin stuck behind the head of glans penis. It happens more frequently in uncircumcised gentlemen. Today we will talk more details on the etiology and the proper management of thisContinue reading “Paraphimosis: True Urologic emergency”

Circumcision stapler

Circumcision Stapler: A better way for circumcision

Today, I’m going to introduce you a novel circumcision technique that’s so-called a Circumcision stapler. Circumcision operation is one of the most frequent operations I have ever done at Urology clinic. It has been reported on a significant decreasing risk of sexually transmitted disease such as genital ulcer disease, human papillomavirus (HPV) or even humanContinue reading “Circumcision Stapler: A better way for circumcision”

Intermittent Testicular Torsion: Difficult clinical diagnosis

Intermittent Testicular Torsion: Difficult clinical diagnosis

I have been seeing several cases related to the Intermittent testicular torsion’s patients throughout my practicing in urological.  Patients were always at the emergency room with a severe testicular pain. The pain was extremely bad, so bad to make patient couldn’t do anything besides laid down on the bed and sobbing to get help. First,Continue reading “Intermittent Testicular Torsion: Difficult clinical diagnosis”


Something went wrong. Please refresh the page and/or try again.

Leave a Reply

%d bloggers like this: